Effect of intravenous nitroglycerin therapy on erythrocyte antioxidant enzymes

Effect of intravenous nitroglycerin therapy on erythrocyte antioxidant enzymes.

Intravenous nitroglycerin (GTN) has been used as an anti-ischemic agent for the therapy of unstable and post-infarction angina. Nitric oxide (NO) and S-nitrosothiols constitute the biologically active species formed via nitroglycerin bioactivation. Increased levels of reactive oxygen species can diminish the therapeutic action of organic nitrates by scavenging donated NO and oxidizing tissue th...

Effect of Intravenous Nitroglycerin

This study was performed to determine whether nitroglycerin (NG) can increase collateral flow to ischemic myocardium and reduce ultimate infarct size. Permanent occlusion of the mid-circumflex coronary artery was produced in 43 previously instrumented conscious dogs and within 3 minutes, 6-hour intravenous infusions were begun of saline (controls, n = 18), NG in doses to reduce mean arterial pr...

Effect of long-term onion (Allium cepa) feeding on antioxidant enzymes in goat erythrocyte

The effect of long-term onion consumption on red blood cell antioxidant enzymes [glucose-6-phosphate dehydrogenase (G6PD), superoxide dismutase (SOD) and glutathione peroxidase (GPx)], were measured. The relationship of these enzymes with PCV and hemoglobin (Hb) concentrations was also determined. Twelve adult female goats were used for the experiment and randomly assigned to three groups. Anim...

Erythrocyte Antioxidant Enzymes in Hyperlipoproteinemia

Erythrocyte Antioxidant Enzymes in Overweight Thai

The specific activities of antioxidant enzymes, [eg superoxide dismutases (SOD), glutathione peroxidase (GPX) and catalase (CAT)], anthropometric measurements, including waist/hip ratio of 48 male and 167 female overweight persons (body mass index (BMI) ≥25.0 kg/m) compared with a 26 male and 80 female control group (BMI = 18.5-24.9 kg/m) of Thai volunteers who attended the Out-patient Departme...